Introduction of Tryptophan Solution
Tryptophan is an essential amino acid for mammals, existing as white to yellowish-white crystals or crystalline powder. L-Tryptophan is a crucial component in the formation of body proteins, participating in the regulation of protein synthesis and fat metabolism. It also has a very close relationship with the metabolic regulation of other substances, such as carbohydrates, vitamins, and trace elements. Tryptophan can be produced through microbial fermentation using glucose derived from the saccharification of starch milk (from grains like corn, wheat, and rice) as a carbon source, typically by microorganisms such as Escherichia coli, Corynebacterium glutamicum, and Brevibacterium flavum.
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Tryptophan Production Process
Starch
01
Primary processing of grain
Primary processing of grain
Starch produced from grain crops such as corn, wheat, or rice is used as raw material and processed through liquefaction and saccharification to obtain glucose.
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02
Cultivation of Microorganisms
Cultivation of Microorganisms
The fermentation environment is adjusted to a condition suitable for the growth of the microorganisms, and inoculation and cultivation are carried out, controlling pH, temperature, and aeration to ensure optimal growth of the microorganisms.
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03
Fermentation
Fermentation
The well-cultivated microorganisms are added to the sterilized fermentation tank, along with antifoam agents, ammonium sulfate, etc., and cultivated under suitable fermentation conditions. After the fermentation is completed, the fermentation liquid is inactivated and the pH is adjusted to 3.5 to 4.0. Then it is transferred to a fermentation liquid storage tank for later use.
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04
Separation and Purification
Separation and Purification
In industrial production, ion exchange is commonly used. The fermentation liquid is diluted to a certain concentration, then the pH of the fermentation liquid is adjusted with hydrochloric acid. Tryptophan is adsorbed by ion exchange resin, and finally, the tryptophan is eluted from the resin with an eluent to achieve the purpose of concentration and purification. The separated tryptophan still needs to go through processes such as crystallization, dissolution, decolorization, recrystallization, and drying.
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Tryptophan
Application Fields of Tryptophan
Feed Industry
Tryptophan promotes the feeding of animals, reduces stress reactions, improves animal sleep, and can also increase antibodies in fetuses and young animals, and improve the lactation of dairy animals. It reduces the use of high-quality protein in the daily diet, saving feed costs, and reduces the use of protein feed in the diet, saving formulation space, etc.
Food Industry
Tryptophan can be used as a nutritional supplement, food fortifier, or preservative, in the production of nutritional supplements for women and children, such as milk powder, fermentation of bread and other baked goods, or preservation of fish and meat products. In addition, tryptophan can also serve as a biosynthetic precursor for the fermentation production of the food color indigotin, to increase the production of indigo.
Pharmaceutical Industry
Tryptophan is commonly used in the fields of health products, bio-pharmaceuticals, and pharmaceutical raw materials. Tryptophan can enhance immunity and is used in the synthesis of drugs for the treatment of schizophrenia and sedative-antidepressant medications. Tryptophan can be used directly in clinical settings as a drug, or as a precursor in the production of some drugs, such as prodigiosin.
Plant-based beverage
Plant-based vegetarian
Dietary-supplement
Baking
Pet food
Deep sea fish feed
Lysine Production Projects
30,000 ton lysine production project, CIS
30,000 ton Lysine Production Project, CIS
Location: CIS
Capacity: 30,000 ton/year
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We provide customers with full life cycle engineering services such as consulting, engineering design, equipment supply, engineering operation management, and post renovation services.
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Frequently Asked Questions
Wet Milling Process of Corn Starch
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These days, cornstarch is made by a process called wet milling.
Routine Use of Purifier
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In the complete flour mill plant, the flour purifier is an indispensable part. After carefully debugging and operation adjustment, the working condition of the purifier should be patrolled frequently during the production process, which is also very important for the stability of the flour quality and the service life of the flour purifier.
Corn Gluten Meal Usage
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Corn Gluten Meal is a protein-rich product which extract from maize, with the process of steeping, separating, drying separation and condensing the gluten liquid, drying it.
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