Tryptophan Production Solution
Tryptophan (Trp) is an important essential amino acid that the human body cannot synthesize on its own and must be obtained through diet or external supplementation. It is a critical component in protein synthesis and serves as a precursor to various bioactive substances (such as serotonin and melatonin), playing a vital role in neurological regulation, immune function, and metabolic balance. The production of tryptophan primarily involves three technical approaches: microbial fermentation, chemical synthesis, and enzymatic catalysis. Among these, the predominant method is microbial fermentation.
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Process Flow of Microbial Fermentation Method
Starch
Tryptophan
Tryptophan: Product Forms and Core Functions
Main Product Forms of Tryptophan
1. L-Tryptophan
The naturally occurring bioactive form, widely used in pharmaceuticals, food, and feed additives.
Common dosage forms: powder, capsules, tablets.
2. Tryptophan Derivatives
5-Hydroxytryptophan (5-HTP): A direct precursor for serotonin synthesis, used for anti-depression and sleep improvement.
Melatonin: Produced through tryptophan metabolism, regulates the sleep-wake cycle.
3. Industrial-Grade Tryptophan
Used in animal feed (e.g., for pigs and poultry) to promote growth and reduce stress.
Core Functions
1. Neurological Regulation and Mental Health
Synthesizes serotonin ("happiness hormone") to improve depression, anxiety, and mood disorders.
Converts to melatonin to regulate sleep patterns and alleviate insomnia.
2. Protein Synthesis and Metabolism
As an essential amino acid, it participates in the body’s protein construction, promoting muscle growth and repair.
3. Immune Regulation
Supports immune cell function and reduces inflammatory responses.
4. Animal Nutrition
When added to feed, it reduces stress-related behaviors in animals (e.g., tail-biting in pigs) and improves feed efficiency.
1. L-Tryptophan
The naturally occurring bioactive form, widely used in pharmaceuticals, food, and feed additives.
Common dosage forms: powder, capsules, tablets.
2. Tryptophan Derivatives
5-Hydroxytryptophan (5-HTP): A direct precursor for serotonin synthesis, used for anti-depression and sleep improvement.
Melatonin: Produced through tryptophan metabolism, regulates the sleep-wake cycle.
3. Industrial-Grade Tryptophan
Used in animal feed (e.g., for pigs and poultry) to promote growth and reduce stress.
Core Functions
1. Neurological Regulation and Mental Health
Synthesizes serotonin ("happiness hormone") to improve depression, anxiety, and mood disorders.
Converts to melatonin to regulate sleep patterns and alleviate insomnia.
2. Protein Synthesis and Metabolism
As an essential amino acid, it participates in the body’s protein construction, promoting muscle growth and repair.
3. Immune Regulation
Supports immune cell function and reduces inflammatory responses.
4. Animal Nutrition
When added to feed, it reduces stress-related behaviors in animals (e.g., tail-biting in pigs) and improves feed efficiency.
Infant formula milk powder
Pharmaceuticals and health products
Dietary-supplement
Feed
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