Lysine Production Solution
Lysine is an essential basic amino acid that the human body cannot synthesize and must obtain from the diet. It finds extensive applications in the food, pharmaceutical, and feed industries. Industrially, lysine is produced through microbial fermentation, primarily utilizing starchy raw materials like wheat as the chief carbon source. The production process encompasses several stages, including pretreatment, fermentation, extraction, and purification.
We provide a full range of engineering services, including project preparatory work, overall design, equipment supply, electrical automation, installation guidance and commissioning.
Lysine Production Process
Grain
01
Pretreatment Stage
Pretreatment Stage
Raw materials such as wheat are transported and crushed, then mixed with hot water to form a starch slurry. This slurry is subsequently processed through liquefaction and saccharification to obtain a sugar solution for fermentation.
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02
Fermentation Stage
Fermentation Stage
The sugar solution from the pretreatment is introduced into a fermentation tank containing lysine-producing bacteria. Sterile air is supplied, and conditions such as temperature, pH, and dissolved oxygen levels are regulated to facilitate bacterial fermentation and lysine production. Throughout the fermentation process, energy sources like electricity and cooling water are continuously replenished, and nutrients such as ammonia water are added to ensure smooth operation.
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03
Extraction Stage
Extraction Stage
Once fermentation is complete, the fermentation broth undergoes centrifugation and filtration to separate bacterial cells and impurities, resulting in a clear liquid containing lysine. Ion exchange resin adsorption and elution techniques are then applied to extract lysine from the broth.
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04
Purification Stage
Purification Stage
The extracted lysine solution is concentrated, crystallized, centrifuged, and dried to produce high-purity lysine. During the drying process, temperature and humidity are carefully controlled to maintain the quality and stability of the final lysine product.
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Lysine
COFCO Technology & Industry Technical Advantages
Strain Innovation and Engineering Integration Capabilities
Through metabolic engineering techniques, random mutation and screening of strains have been conducted, successfully developing recombinant high-yield strains that significantly enhance lysine production.
Engineering Design and EPC (Engineering, Procurement, and Construction) Advantage: Leveraging COFCO Technology & Industry's expertise in engineering design, we achieve full-chain coverage from strain development to electromechanical EPC, maintaining a leading position in the field of amino acid fermentation in China.
Policy Orientation and Market Expansion
Serving National Strategies: Our technological achievements directly support the national "Belt and Road" development strategy, facilitating the expansion of amino acid deep-processing businesses in overseas markets (e.g., Southeast Asia and the Middle East).
Diverse Application Scenarios: Our products cater to the feed, pharmaceutical, and food industries, meeting customized demands for lysine purity (e.g., pharmaceutical grade ≥99.5%) and functionality across different clients.
Technical Collaboration and Resource Integration
Industry-Academia-Research Collaboration: Long-term partnerships with institutions like Jiangnan University have been established to jointly advance strain modification and process optimization, accelerating technological iteration and achievement transformation.
Circular Economy Model: Byproducts such as fermentation waste liquid are repurposed to produce bacterial cellulose or compound fertilizers, achieving a resource utilization rate of 92%, aligning with green manufacturing trends.
Plant-based beverage
Nutritional supplement
Feed
Baking
Cosmetic ingredient
Deep sea fish feed
Lysine Production Project
30,000 ton lysine production project, CIS
30,000 ton Lysine Production Project
Location:
Capacity: 30,000 ton/year
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Full Lifecycle Service
We provide customers with full life cycle engineering services such as consulting, engineering design, equipment supply, engineering operation management, and post renovation services.
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Frequently Asked Questions
CIP Cleaning System
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CIP cleaning system device is a non-decomposable production equipment and a simple and safe automatic cleaning system. It is used in almost all food, beverage and pharmaceutical factories.
A Guide to Pressed and Extracted Oils
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There are significant differences between the pressed oil and extracted oil in terms of processing techniques, nutritional content, and raw material requirements.
Scope of Technical Service for Grain-based Biochemical Solution
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At the core of our operations are internationally advanced strains, processes, and production technologies.
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