Introduction of Glutamic Acid Solution
Glutamic Acid is an important non-essential amino acid widely found in nature and one of the primary components of proteins. Its sodium salt form, sodium glutamate (MSG, monosodium glutamate), is the most common food additive. Glutamic acid and its derivatives have extensive applications in pharmaceuticals, food, cosmetics, and agriculture.
The biological fermentation production of glutamic acid utilizes starchy raw materials (such as corn and cassava) as the primary carbon source, achieving industrial-scale production through four main stages: pretreatment, fermentation, extraction, and purification.
The biological fermentation production of glutamic acid utilizes starchy raw materials (such as corn and cassava) as the primary carbon source, achieving industrial-scale production through four main stages: pretreatment, fermentation, extraction, and purification.
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Biological Fermentation Process Flow
Corn
Glutamic Acid
COFCO Technology & Industry Technical Advantages
Innovations in Enzymatic Processes
High Purity and Green Production: Utilizing dual-enzyme cascade technology to significantly reduce byproduct formation, aligning with international environmental standards.
Breakthrough in Immobilization Technology: Employing magnetic nano-carriers to enable enzyme reuse, promoting continuous production and reducing overall energy consumption.
Innovations in Synthetic Biology
Strain Optimization: Using gene-editing technologies (e.g., CRISPR) to enhance Corynebacterium glutamicum, improving acid production efficiency and substrate utilization.
Multi-Enzyme Synergy: Developing multi-enzyme cascade systems, such as semi-synthetic artemisinin production, to expand the manufacturing of high-value derivatives (e.g., D-pyroglutamic acid).
Circular Economy Integration
Resource Utilization: Converting fermentation waste liquid into bacterial cellulose production, achieving wastewater COD reduction and resource regeneration.
High Purity and Green Production: Utilizing dual-enzyme cascade technology to significantly reduce byproduct formation, aligning with international environmental standards.
Breakthrough in Immobilization Technology: Employing magnetic nano-carriers to enable enzyme reuse, promoting continuous production and reducing overall energy consumption.
Innovations in Synthetic Biology
Strain Optimization: Using gene-editing technologies (e.g., CRISPR) to enhance Corynebacterium glutamicum, improving acid production efficiency and substrate utilization.
Multi-Enzyme Synergy: Developing multi-enzyme cascade systems, such as semi-synthetic artemisinin production, to expand the manufacturing of high-value derivatives (e.g., D-pyroglutamic acid).
Circular Economy Integration
Resource Utilization: Converting fermentation waste liquid into bacterial cellulose production, achieving wastewater COD reduction and resource regeneration.
MSG
Meat products
Dietary-supplement
Biological reaction buffer
Soy sauce
Feed
Lysine production project
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